abstract：:Spitz nevus (SN) and Spitzoid malignant melanoma (SMM) represent benign and malignant counterparts at both ends of the spectrum of Spitzoid lesions. Atypical Spitzoid neoplasm (ASN) is a poorly defined and characterized category of melanocytic tumors with histologic features of both benign Spitz nevi and malignant mel...

journal_title：Seminars in cutaneous medicine and surgery

authors： Miteva M,Lazova R

更新日期：2010-09-01 00:00:00

abstract：:Phototherapeutic modalities, including narrowband-UVB, broadband-UVB, PUVA photochemotherapy, and excimer laser therapy are valuable tools that can be used for photoresponsive dermatoses in children. As a systematically safer alternative compared with internal agents, including the prebiologic and biological therapies...

journal_title：Seminars in cutaneous medicine and surgery

authors： Pugashetti R,Koo J

更新日期：2010-06-01 00:00:00

abstract：:The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...

journal_title：Seminars in cutaneous medicine and surgery

authors： Warren RB,Griffiths CE

更新日期：2010-03-01 00:00:00

abstract：:Lasers, both in single and multiple wavelength designs, have recently been introduced to enhance the results of liposuction. Safe parameters of fluence and temperature have not yet been described. In this study, I describe a series of laser lipolysis patients treated with a dual wavelength (1064/1319 nm) laser where i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Salzman MJ

更新日期：2009-12-01 00:00:00

abstract：:Dermoscopy increases the clinician's diagnostic accuracy by as much as 30% over that of unaided visual clinical inspection alone and has been confirmed in 3 separate evidence-based publications using a meta-analysis of the literature. It can be viewed as an in vivo bridge between clinical morphology and histopathology...

journal_title：Seminars in cutaneous medicine and surgery

authors： Braun RP,Rabinovitz H,Tzu JE,Marghoob AA

更新日期：2009-09-01 00:00:00

abstract：:This review highlights melanoma trends observed among African-, Asian-, Latino- and Native-American populations. Melanoma is the most lethal form of skin cancer, accounting for about 75% of all skin cancer deaths. Generally, incidence rates increase with age, peak after age 40, and are greater in men than women. Howev...

journal_title：Seminars in cutaneous medicine and surgery

authors： Shoo BA,Kashani-Sabet M

更新日期：2009-06-01 00:00:00

abstract：:Hair disorders include hair loss, increased hair growth, and hair structure defects with increased breakage, as well as unacceptable cosmetic appearance, such as reduced shine, strength, curliness, and elasticity. It is the task of the dermatologist to choose the right diagnostic tool depending on the suspected clinic...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hillmann K,Blume-Peytavi U

更新日期：2009-03-01 00:00:00

abstract：:Lasers frequently are used by dermatologists for their multiple aesthetic applications, but they also can be used to treat a variety of medical dermatology conditions. Conditions such as acne vulgaris, psoriasis, and vitiligo can all be successfully treated with laser, thereby providing the patient with additional the...

journal_title：Seminars in cutaneous medicine and surgery

authors： Railan D,Alster TS

更新日期：2008-12-01 00:00:00

abstract：:Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kempiak SJ,Uebelhoer N

更新日期：2008-09-01 00:00:00

abstract：:In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kunz M

更新日期：2008-03-01 00:00:00

abstract：:The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Migden M,Chavez-Frazier A,Nguyen T

更新日期：2008-03-01 00:00:00

abstract：:The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...

journal_title：Seminars in cutaneous medicine and surgery

authors： Sugarman JL

更新日期：2007-12-01 00:00:00

abstract：:This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Carr DR,Houshmand E,Heffernan MP

更新日期：2007-09-01 00:00:00

abstract：:Deep morphea encompasses a variety of clinical entities in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia, or superficial muscle. Morphea profunda, eosinophilic fasciitis, and disabling pansclerotic morphea of children are included in this group, but overlapping of the extent and dep...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bielsa I,Ariza A

更新日期：2007-06-01 00:00:00

abstract：:In dermatology, botulinum toxin is now most often used to reduce dynamic facial creases and treat primary focal hyperhidrosis. The exemplary safety record of this medication is such that after nearly 2 decades, it is not known to have any long-term adverse events. Transient adverse events, such as mild injection pain,...

journal_title：Seminars in cutaneous medicine and surgery

authors： Pena MA,Alam M,Yoo SS

更新日期：2007-03-01 00:00:00

abstract：:Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Jackson JM

更新日期：2006-12-01 00:00:00

abstract：:Nonsurgical procedures have become very popular for the rejuvenation of the aging face. Trends now are for less invasive procedures as well as for more preventative intervention to slow the damage from ultraviolet light and environmental factors, as well as from intrinsic aging. The goal of these procedures is to elim...

journal_title：Seminars in cutaneous medicine and surgery

authors： Lupo MP

更新日期：2006-09-01 00:00:00

abstract：:Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Yang A,Kerdel FA

更新日期：2006-06-01 00:00:00

abstract：:Hair shaft abnormalities are fascinating and can provide a diagnostic challenge. Current knowledge of structural changes in hair has been amplified by scanning and transmission electron microscopy (SEM and TEM). Dermatologists using the light microscope and polarization in the office can diagnose the great majority of...

journal_title：Seminars in cutaneous medicine and surgery

authors： Whiting DA,Dy LC

更新日期：2006-03-01 00:00:00

abstract：:"Venous disease consists of a spectrum with significant medical and economic morbidities. For lack of exposure, however, it is a poorly understood subject. The evaluation and approach to diagnosing venous disease requires a firm understanding of venous anatomy and pathophysiology. With a targeted history and physical,...

journal_title：Seminars in cutaneous medicine and surgery

authors： Nguyen TH

更新日期：2005-12-01 00:00:00

abstract：:Dermatologists will enter into a number of different contracts during their professional careers. It is important that in each agreement they enter, dermatologists reap the benefits that they aspire for and understand the consequences of each provision. This article addresses just a few of the different issues that ar...

journal_title：Seminars in cutaneous medicine and surgery

authors： Fanburg JD,Leone AM

更新日期：2005-09-01 00:00:00

abstract：:Artecoll was developed about 20 years ago and underwent a number of production changes until it recently became FDA approved under the new name of Artefill. This product contains 20% polymethyl methacrylate (PMMA) microspheres with a diameter of 30 to 40 microm, which are suspended in a 3.5% atelo-collagen solution. T...

journal_title：Seminars in cutaneous medicine and surgery

authors： Haneke E

更新日期：2004-12-01 00:00:00

abstract：:Although the majority of hemangiomas of infancy can be expected to follow a benign course, a significant subset may result in serious complications. Recently, hemangiomas of segmental morphology, or those which are large, plaque-like, and patterned in distribution, have been recognized as important markers for potenti...

journal_title：Seminars in cutaneous medicine and surgery

authors： Metry DW

更新日期：2004-06-01 00:00:00

abstract：:The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium. The etiologic, pathogenic, clinical and, in particular, the histopathologic attributes of the most important intraepidermal...

journal_title：Seminars in cutaneous medicine and surgery

authors： Cassandra M,Morgan M

更新日期：2004-03-01 00:00:00

abstract：:Closing surgical defects of the external ear poses unique challenges because of the convoluted shape and thin tethered skin. Choice of repair is often dictated by the site of the wound. If the defect is central and anterior with intact cartilage, most defects will do well by second intention healing or grafting. If th...

journal_title：Seminars in cutaneous medicine and surgery

authors： Olbricht S,Liégeois NJ

更新日期：2003-12-01 00:00:00

abstract：:The ThermaCool TC system is a radiofrequency device capable of delivering higher energy fluences to a greater volume of tissue than nonablative lasers, with no epidermal injury. It has been successful in treating periorbital rhytides and lifting eyebrows. Given these positive finding for treatment of the upper face, t...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hsu TS,Kaminer MS

更新日期：2003-06-01 00:00:00

abstract：:There has been a dramatic increase in the incidence of malignant melanoma in most parts of the world. Because the tumor thickness is the most important prognostic factor for the prognosis of the malignant melanoma, the early detection of thin melanomas is essential. Dermatoscopy allows the physician to discriminate be...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stolz W,Semmelmayer U,Johow K,Burgdorf WH

更新日期：2003-03-01 00:00:00

abstract：:In an attempt to limit the prolonged postoperative healing associated with ablative laser skin resurfacing and in response to growing public interest in less invasive treatment modalities, nonablative laser and light source technology was developed. Over the past few years, several clinical and histologic research stu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Alster TS,Lupton JR

更新日期：2002-12-01 00:00:00

abstract：:The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stuetz A,Grassberger M,Meingassner JG

更新日期：2001-12-01 00:00:00

abstract：:Topical retinoic acid was introduced for acne treatment three decades ago. Since that time, researchers have discovered thousands of retinoids, originally defined as chemical analogs of vitamin A. After the identification of nuclear retinoid receptors in 1987, the definition of this class expanded to include molecules...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bershad S

更新日期：2001-09-01 00:00:00

abstract：:Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...

journal_title：Seminars in cutaneous medicine and surgery

authors： Dinehart S

更新日期：2000-09-01 00:00:00

abstract：:Mycosis fungoides is a peripheral non-Hodgkin's T-cell neoplastic process, representing the most common type of primary cutaneous malignant lymphoma. Neoplastic lesions classically show skin predilection and characteristic clinical and histologic features in patch, plaque, and tumor stages. In addition, several clinic...

journal_title：Seminars in cutaneous medicine and surgery

authors： Howard MS,Smoller BR

更新日期：2000-06-01 00:00:00

abstract：:Perioral dermatitis is a unique skin disorder of childhood. Its exact origin is unknown; it is probably an idiosyncratic response to exogenous factors such as the use of a topical fluorinated corticosteroid or other substances on the face. It is uncommon but not rare. The age of affected children has ranged from 7 mon...

journal_title：Seminars in cutaneous medicine and surgery

authors： Laude TA,Salvemini JN

更新日期：1999-09-01 00:00:00

abstract：:Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...

journal_title：Seminars in cutaneous medicine and surgery

authors： Krauss MC

更新日期：1999-06-01 00:00:00

abstract：:This review highlights important considerations in obtaining good skin biopsy specimens to optimize results of direct immunofluorescence (IF) studies and also summarizes the various patterns of cutaneous IF deposition and their associated diagnoses. IF findings of immunobullous diseases, lupus erythematosus, vasculiti...

journal_title：Seminars in cutaneous medicine and surgery

authors： Morrison LH

更新日期：1999-03-01 00:00:00

abstract：:Thalidomide, originally marketed as a sedative, was introduced in West Germany in 1956 and in numerous other countries soon thereafter. In part because it did not impair coordination or respiratory function, the drug rapidly became extremely popular. By 1961, however, there were mounting reports of phocomelia and othe...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stirling DI

更新日期：1998-12-01 00:00:00

abstract：:Dermatologic manifestations are among the most common signs of systemic lupus erythematosus (SLE). The Hopkins Lupus Cohort study is a prospective study in which patients with SLE are seen on a quarterly basis for measurement of disease activity, laboratory tests, and assessment of morbidity and quality of life. This ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petri M

更新日期：1998-09-01 00:00:00

abstract：:Cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. Each has its own etiology and unique clinical characteristics, but all involve the dysregulation of connective tissue metabolism, in particular, the activation of dermal fibr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Liu B,Connolly MK

更新日期：1998-03-01 00:00:00

abstract：:Oral mucosal bullous/desquamative/ulcerative diseases involve immunopathological mechanisms that account for loss of adhesion between contiguous keratinocytes or to structures within the basal lamina. Some are antibody mediated, in which specific adhesion molecules of the desmosome, hemidesmosome, and basement membran...

journal_title：Seminars in cutaneous medicine and surgery

authors： Eversole LR

更新日期：1997-12-01 00:00:00

abstract：:Infections with organisms of the genus Bartonella, for many years important only in South and Central America, have assumed significance in developing countries, especially in conjunction with the advent of the pandemic of the human immunodeficiency virus infection. New molecular and culture techniques have determined...

journal_title：Seminars in cutaneous medicine and surgery

authors： Wong R,Tappero J,Cockerell CJ

更新日期：1997-09-01 00:00:00